Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, such as evolocumab and alirocumab, are monoclonal antibodies that reduce LDL cholesterol by 46%-73% and provide significant cardiovascular benefits, especially in high-risk patients
They can be useful for breakthrough constipation but should be used under medical supervision if needed long-term
Common symptoms in LBD and FTD include delusion, hallucination, aggression, depression, anxiety, euphoria, apathy, disinhibition, appetite changes, and sleep disturbances (van de Beek et al., 2022
Early discussions of potential problems with function, prostheses, oral fungal infection, and lesion recurrence may ensure patient compliance