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We moved away from IV because intracellular NAD+ levels, which is where the benefit actually happens, do not reliably increase with IV administration

Therefore, we stated that the proposed conversion factor would be adjusted by the difference between the 0.37 percent estimate of pass-through spending for CY 2025 and the 0.59 percent estimate of proposed pass-through spending for CY 2026, resulting in a proposed decrease to the conversion factor for CY 2026 of 0.22 percentage point

For any multi-use research protocol, BAC water isn't just a recommendation

Protects cells against oxidative damage caused by scavenging free radicals