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doi:10.1016/j.jaci.2015.10.004 Zinman, B., Philis-Tsimikas, A., Cariou, B., Handelsman, Y., Rodbard, H

Melatonin synthesis was evaluated by measuring urinary 6-sulfatoxymelatonin, the primary metabolite of melatonin, which increased 1.6-fold in the Epitalon group relative to placebo

Portion sizes may gradually increase, or higher-calorie foods may be reintroduced more frequently