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Description

Liquid research solution

By initiating the breakdown of L-tyrosine in the proximal region of the small intestine with consequent reduction of the quantity reaching the colon and by competing with the native gut microbiota in the colon implicated in p-cresol generation from L-tyrosine, the therapeutic strain exerts its activity in CKD patients

271,272 Additionally, hyperglycemia-induced oxidative and nitrosative stress activates poly(ADP-ribose) polymerase (PARP), a nuclear enzyme involved in DNA repair