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Name: eli lilly retatrutide study Lilly's cuts weight by 17% in diabetes trial Eli Lilly Preparing Retatrutide Applications
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Its a small-molecule NNMT inhibitor, blocking an enzyme (nicotinamide N-methyltransferase) involved in fat cell metabolism

Caspase 1 (CASP1), when activated, cleaves gasdermin D (GSDMD), producing the pore-forming protein N-GSDMD, and also cleaves pro-IL1B and pro-IL18 into their mature forms [138]

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