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However, Phase 2 trials are not always powered or designed to detect rare psychiatric adverse events, and longer-term Phase 3 data which would provide a more comprehensive safety profile had not been fully published at the time of writing

It may also help through weight loss, since losing weight can improve insulin resistance

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Some people, especially those with a history of disordered eating, chronic stress, hormone imbalances, or certain medical conditions, may find that fasting worsens their symptoms or creates an unhealthy relationship with food