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The mechanism underlying the anti-inflammatory properties of SGLT-2i could be a downstream effect of its ability to lower uric acid and insulin production [97]

Further, while dietary l-carnitine supplementation induced no differences in fecal transformation of the first step of the l-carnitineBBTMA/TMAO metaorganismal pathway in either omnivores or vegans/vegetarians, dietary l-carnitine provision induced enhanced fecal microbial transformation of the second microbial step in the overall pathway (i.e., d 9 -BBd 9 -TMA) in omnivores ( P = 0.02), but not vegans/vegetarians ( P = 0.69) (Figure 5C)

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