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Safety: There is insufficient evidence regarding safety in humans
We induced abdominal compartment syndrome (intra-abdominal pressure in thiopental-anesthetized rats at 25 mmHg (60 min), 30 mmHg (30 min), 40 mmHg (30 min), and 50 mmHg (15 min) and in esketamine-anesthetized rats (25 mmHg for 120 min)) as a model of multiple occlusion syndrome
Mechanisms of action: NF-B inhibition: KPV inhibits the activation of nuclear factor kappa-B (NF-B), the master regulator of the inflammatory response
After reconstitution: Refrigerate the solution and use within 30 days
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