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Diabetes remains the leading cause of chronic kidney disease in most countries, said Vlado Perkovic, MBBS, PhD, FRACP, FASN, FAHMS, Provost and Health and Scientia Professor, University of New South Wales, Sydney, Australia

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Using this experimental paradigm, we next determined whether SIRT3 overexpression in HSCs suppresses aging-associated inflammation and tissue function decline by giving rise to progeny that go into the circulation