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For researchers studying metabolic regulation, retatrutide offers a uniquely multifaceted pharmacological tool

Seeley, University of Michigan, Ann Arbor, Michigan, USA

GLP1RAs can inhibit neutral lipid accumulation, ROS generation, and (NADPH oxidase 4) NOX-4 expression in rat cardiomyocytes, thereby migrating interleukin-1 (IL-1 ) induced ROS production [57]