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TRT is a subset of HRT

Many patients see improvement in: Age spots Sun-related pigmentation Acne scars Uneven patches However, the degree of improvement depends on skin type, severity of pigmentation, and treatment consistency

What matters most for treatment success is consistent weekly administration, proper dose escalation, and adherence to lifestyle modifications including diet and physical activity, rather than the specific anatomical location chosen for injection

It was reported that NSAID usage varies with both sex and age [20, 21], and since sex hormones can affect various physiological responses, we divided the subjects into eight groups based on sex, age, and NSAID usage