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Although this amount is small compared with the annual economic losses from tobacco ($1.4 trillion per year) and may appear insignificant compared with the 8 million deaths attributable to tobacco each year, these environmental costs should not be downplayed as these are accumulating and are preventable, Sy said in a news release

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In addition to directly activating various inflammatory cells such as MCs, eosinophils, and alveolar macrophages to infiltrate and recruit them in the airways, these cytokines can also aggravate AHR