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Others have used Bayesian parameter estimation, but this was computationally too costly for the scale and complexity of our model

Glycation, the process of bonding a protein with a sugar molecule, has been shown to reduce the allergenicity of TM in several studies: In a study using a mast cell degranulation system and a murine model, glycated TM with smaller saccharides led to significantly lower histamine release, reduced IgE levels, and milder allergic symptoms

Miller CG, Holmgren A, Arner ESJ, and Schmidt EE

For her part, though, Big is aware of the controversial nature of her black identity claims, and wants others to know she's not trying to be offensive