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In rats, long-term low-dose PS-NPs exposure reduced amygdalar metabolites-N-acetylserotonin, N-acetyl-L-tyrosine, and 4-aminobutyric acid, suggesting impaired neurotransmitter metabolism (Jiang et al., 2023)
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Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential
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