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But users of the injection medications may also face increased risks for pancreatitis and kidney conditions, among other illnesses

These are actual GLP-1 receptor agonists, not supplements

Published clinical guidelines from organizations including the American Society of Metabolic and Bariatric Surgery and the Obesity Medicine Association have identified GLP-1 receptor agonists as appropriate pharmacological interventions in patients with a BMI of 30 or above (classified as obesity), or BMI of 27 or above with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidemia, or obstructive sleep apnea - the same criteria framework used by the FDA in evaluating GLP-1 medications for their obesity management indications

By contrast, retrograde axonal transport is from the synapses to the cell body