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[12] [13] Many patients with type 2 diabetes take metformin alongside newer agents like Mounjaro, which may increase their overall risk of B12 deficiency

The increase in vitamin B12 levels in non-responders was significant but much lower than the increase in levels among the responders

Some researchers use a small thermometer inside the fridge to monitor temperature

Questions remaining include optimal human dosing, long-term safety, effects across different populations, interactions with diet and exercise, and whether benefits extend beyond weight loss to improvements in cardiometabolic disease outcomes