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Furthermore, stable conjugation and stealth coatings, like polyethylene glycol (PEG), allow for reduced immune clearance and prolonged circulation [33]

We cant say that GLP-1s are actually causing these symptoms, says Neil K

The GLP-1s and GIPs approved by the FDA for weight loss are: Saxenda (liraglutide), Wegovy (semaglutide), and Zepbound (tirzepatide)

In patients with elevated concentration of chylomicron triglycerides and VLDL triglycerides (polygenic chylomicronaemia), diet is very important, although more difficult to implement, as it should be targeted at reduction of chylomicron synthesis in the intestinal epithelium, so fat intake must be very limited ( 2.3 mmol/l (200 mg/dl), treatment is always initiated with a statin (atorvastatin or rosuvastatin)