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Preclinical data also indicate potential anticancer effects independent of weight loss, such as modulation of tumor cell metabolism and inflammation, as well as reprogramming of tumor-associated macrophages toward anti-tumor (M1-like) phenotypes and enhanced cytotoxic T-cell infiltration in animal models

Levisohn L, Cronin-Golomb A, Schmahmann JD

We observed a marked decrease of gastric epithelial cell proliferation rates, protection against parietal cell death and a 90% reduction of gastritis, accompanied by normalized expression levels for all (pro-inflammatory) cytokines, confirming the suppression of the host immune response elicited by Helicobacter infection