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In September 2025, Eli Lilly canceled one of its two Phase 2 bimagrumab trials, though the company cited strategic business reasons rather than safety signals, and a second trial in non-diabetic obesity patients continued

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Family or personal history of melanoma or unusual moles Your dermatologist may also perform tests such as: Dermoscopy (onychoscopy), in which your doctor uses an instrument called a dermatoscope to closely look at your nail under a microscope and take detailed pictures of your nail streaks Nail biopsy with histopathology, in which a small piece of your nail is taken to test for cancer How Is Melanonychia Treated

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