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In a phase 2 clinical trial involving 30 MASH patients with advanced fibrosis (NCT02421094), GR-MD-02 had no significant effect on non-invasive biomarkers of liver inflammation or fibrosis after 16 weeks, as measured by magnetic resonance elastography and shear-wave ultrasonic elastography, since histopathology monitoring was not planned for this study

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This is why refrigeration (28C) is specified instead of freezing (20C) for reconstituted peptides

Gentle Movement to Improve Insulin Sensitivity: Incorporate low-impact exercises, such as walking or yoga, into your daily routine