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Immunotherapy approaches are being evaluated for their potential use in Stage 1 (2 islet autoantibodies but normoglycaemia) or Stage 2 (autoantibodies and dysglycaemia) type 1 diabetes to prevent Stage 3 clinical type 1 diabetes, and for the preservation of beta cell function before and shortly after onset of Stage 3 clinical type 1 diabetes [290]

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Possible mechanisms involved in tumorigenesis in offspring derived from oxidatively damaged IVF embryos From the abovementioned 240 differentially expressed proteins, we enriched 58 tumor-related proteins, including 45 upregulated and 13 downregulated proteins, and analyzed tumor-related signaling pathways (Supplementary Tables 3 and 4)