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There is also an increased risk of hypoglycaemia if retatrutide were used alongside insulin or sulfonylureas

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A Hims & Hers spokesperson told Reuters the company does not expect any impact on its business from the FDA's proposal, saying, "There are no GLP-1s compounded by 503B facilities accessible through our platform, and 503B facilities should not currently be compounding GLP-1s because they are not in shortage." Most telehealth companies use 503A pharmacies to fill their personalized compounded doses, said Rosalie Hoyle, a research scientist at health consultancy Avalere, adding the exclusion from the 503B bulks list may not operationally impact current compounding of GLP-1 drugs