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This specific property has become the focus of numerous research strategies, such as the development of senolytic agents like FOXO4-DRI, which selectively disrupt the FOXO4p53 interaction, thereby enabling the targeted elimination of dysfunctional cells

Overall, it is not contradictory that the gut microbiome may be the source of both antigens and adjuvants, making it a trigger and/or amplifying signal for uveitis-specific T cells

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Elevated levels could reflect a protective response to injury rather than a causal factor