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2020 Nov;140:106099

The studies conducted are too small to draw definitive conclusions, according to Daniele Piomelli, Ph.D., the director of the University of California, Irvines Center for the Study of Cannabis

This is because your brain, even at the biological level, is constantly learning through associations

Expansion of the classes of psychoactive substances: The number of psychoactive substance classes has increased from 9 in ICD-10 to 14 in ICD-11, according to a 2022 article by Matone et al., published in the journal Clinical Psychology in Europe , titled Alcohol and Substance Use Disorders Diagnostic Criteria Changes and Innovations in ICD-11: An Overview . The additional substance classes include cannabis, nicotine, caffeine, synthetic cathinones, and MDMA (Methylenedioxymethamphetamine) or related drugs including MDA (3,4-Methylenedioxyamphetamine)