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Through the regulation of these enzymes, polyphenols facilitate chromatin relaxation, hence enhancing accessibility for transcription factors to activate genes that contribute to cellular repair and neuroprotection

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LD50 is a crucial number for determining the safety of any drug, and it is typically determined through animal testing, with known LD50 values for common substances like caffeine and aspirin 4m6s

Botfield HF, Uldall MS, Westgate CSJ, et al