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8.16% placebo at the end of the study) and there wasn't much of a difference between the groups - this brings into question the mechanism behind CV risk reduction The empagliflozin group had small decreases in weight, waist circumference, uric acid level, and blood pressure but small increases in LDL and HDL Rates of hypoglycemia were comparable among study groups About empagliflozin Empagliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor which works by blocking the reabsorption of glucose by the kidney, allowing it to pass out of the body through the urine (usually the kidney reabsorbs all of the filtered glucose)

doi:10.2174/0929867325666180313105949 Amaral FM, Miranda-Vilela AL, Lordelo GS, Ribeiro IF, Daldegan MB, Grisolia CK