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Understanding these side effects is critical for safe, effective use, particularly for beginners who are still adjusting to hormone-based protocols
The American Association of Clinical Endocrinologists/American College of Endocrinology consensus statement also recommends either a GLP-1RA or SGLT2i as a preferred treatment option (either as first-line or, more typically, second-line treatment after metformin) over alternative options such as a dipeptidyl peptidase-4 inhibitor, a thiazolidinedione (TZD), or a sulfonylurea (SU), for patients with T2D and ASCVD, stage 3 CKD, or heart failure with reduced ejection fraction [2]
2013, no statistically significant changes in IGF-1 or fasting glucose were detected versus placebo
They identified a diverse patient population using data from medical and pharmacy claims individuals enrolled in commercial and Medicare Advantage plans
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