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on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals

IV therapy gives the highest blood levels but requires a clinic visit

Reactive O2 species molecules include peroxide (H2O2) and superoxide anions (O2 with unpaired electron) these molecules are very toxic to the cell

Eur J Cancer Prev