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In addition, nausea is believed to result mainly from central mechanisms, in which activation of GLP-1R neurons in the area postrema plays a predominant role rather than from delayed gastric emptying alone 46

(9) Rotondi and colleagues have determined that seronegative autoimmune thyroiditis is a less aggressive form of Hashimotos, but nonetheless, the person may still develop hypothyroidism and even progress to other autoimmune conditions, which may or may not have respective positive antibody blood markers (such as seronegative rheumatoid arthritis)

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