glp 1 intestine Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms GLP-1 and GLP-2 Orchestrate Intestine

Introduction One recent advance in the management of type 2 diabetes has been the development and clinical use of DPP-4 inhibitors and GLP-1 receptor agonists

Semaglutide, other GLP-1 receptor agonists continue taking the world by storm GLP-1 receptor agonists are now being used to treat obese and overweight patients throughout the United States

However, the use of these drugs has been associated with several notable side effects, including malaise, nausea, and emesis, as well as other gastrointestinal issues

While SGLT2is directly target kidney proximal tubular cells, the kidney cell targets for GLP-1 RAs are unclear