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Thus, we may assume that increased levels of all studied genes could be a result of the glutathione depletion triggered by UA application

Furthermore, postmortem studies showed increased BDNF expression in hippocampus after antidepressant treatment [44]

mild fatigue may occur temporarily

Modest Weight-Neutral or Loss Effect: While not a primary weight loss drug, metformin is generally considered weight-neutral and in some cases, can lead to a modest amount of weight loss, which can be an added benefit for many individuals