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however, the prevalence and natural history of diabetic gastroparesis is poorly defined A number of management strategies for patients with type 2 diabetes mellitus specifically target gastric emptying A bidirectional relationship exists between the rate of gastric emptying and glycaemia, such that the rate of gastric emptying is partially modulated by acute changes in blood glucose concentrations In patients with severe diabetic gastroparesis, histological abnormalities are heterogeneous

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