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Additionally, the role of non-classical ferroptosis suppressors (e.g., FSP1, DHODH, and GCH1/BH4) in ADPKD is entirely unexploredwhether these pathways compensate for GPX4 downregulation in cystic kidneys or if their dysfunction exacerbates ferroptosis susceptibility remains unknown, limiting the development of multi-targeted interventions

Alcohol is a known gastric irritant that can independently increase burping, bloating, and digestive discomfort

Increased myocardial extracellular volume is associated with myocardial iron overload and heart failure in thalassemia major

You usually get enough copper from the foods you eat