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Mechanistic studies of these compounds through various researches provide a deeper understanding of their molecular action, paving the way for the development of future therapeutic agents to combat cancer drug resistance ( 5 Plant extract/derived natural bioactive compound targeting apoptotic and associated pathway of cancer cells Resistance to chemotherapy and radiotherapy along with the toxicity associated with these conventional treatment modalities emphasizes the immense need for anticancer strategies that would be not only safer but more effective

4 The subsequent accumulation of proteoglycan aggregates in the IVD results in cross-linking and accretion of advanced glycation end products, which are not easily scavenged from the disc

In HFD-fed mice, they improved the gut barrier function, reduced body weight gain and improved glucose tolerance