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This ring-shaped complex comprises four core subunits: SMC1 (structural maintenance of chromosomes protein 1), SMC3, a kleisin subunit RAD21 and SA1/2 (STAG1/2) (Nasmyth and Haering, 2009
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Certain structural proteins, protein metabolites, and enzymes in the crystalline lens can absorb blue light, which can induce the production of reactive oxygen species (ROS) in the mitochondria of lens epithelial cells and lead to cell apoptosis through the transforming growth factor - /Smad3 signaling pathway
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